Evaluation of small bowel blood flow in healthy subjects receiving low-dose aspirin

Table 1 The evaluation of area under the curve and time intensity curve by ultrasonography before and after taking low-dose aspirin (n = 10)

	Placebo			Rebamipide
	A.D.	95% CI	P-value	A.D.	95% CI	P-value
AUC	-1102.5	-1980.3 to -224.7	0.0194	-152.7	-1604.2-641.6	0.8172
TIC	-148.0	-269.4 to -26.2	0.0225	28.3	-269.0-325.6	0.8343

A.D.: Absolute differences; AUC: Area under the curve, TIC: Time intensity curve.

Table 2 The evaluation of the preventive effect of rebamipide on low-dose aspirin-induced worsened small bowel injury compared with placebo (mean ± SD)

	Placebo	Rebamipide
Erosion	0.5 ± 2.7	0.0 ± 0.0
Petechiae	10.1 ± 53.6	-8.6 ± 15.4
Erythema	-1.0 ± 2.3	-0.6 ± 1.0

Table 3 Number of subjects with small intestinal mucosal breaks

	Placebo	Rebamipide
Mucosal breaks	2	0