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©2010 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2010; 16(48): 6128-6134
Published online Dec 28, 2010. doi: 10.3748/wjg.v16.i48.6128
Published online Dec 28, 2010. doi: 10.3748/wjg.v16.i48.6128
Inclusion criteria | Exclusion criteria |
> 18 yr | Acute pancreatitis due to surgery |
Abdominal pain | Trauma |
Amylase > 3 times upper normal limit | Cancer |
Onset of abdominal pain within 48 h | Inflammatory bowel disease |
APACHE II score > 8 and/or | Stoma |
CRP > 150 and/or | Short bowel |
Peripancreatic fluid collection on CT | Chronic pancreatitis |
MAP (n = 27) | SAP (n = 22) | P | |
Age (yr)1 | 76 (63-85) | 63 (56-77) | 0.042 |
Sex (M:F) | 14:13 | 10:12 | 0.664 |
APACHE II1 | 9 (8-11) | 9 (7-13) | 0.860 |
Aetiology | |||
Biliary | 15 | 16 | 0.248 |
Alcohol | 4 | 3 | 1.000 |
ERCP | 3 | 1 | 0.617 |
Unknown | 5 | 2 | 0.436 |
Duration of pain (h)1 | 34 (21-43) | 25 (22-29) | 0.160 |
Amylase1 | 8.2 (2.7-13.7) | 9.8 (4.3-15.3) | 0.690 |
IL-6 (pg/mL)1 | 100 (55-210) | 275 (158-315) | 0.001 |
CRP (mg/mL)1 | 106 (69-167) | 173 (104-209) | 0.071 |
Tissue factor (pg/mL)1 | 35 (23-50) | 49 (36-101) | 0.035 |
Fibrinogen (g/L)1 | 4.8 (4.4-6.2) | 4.0 (3.8-7.2) | 0.047 |
FVII (ng/mL)1 | 155 (46-294) | 136 (88-296) | 0.608 |
Time point1 | AUC | P | Cut-off TF (pg/mL) | Sensitivity | Specificity | PLR | NLR |
0 | 0.679 | 0.035 | 32 | 86 | 48 | 1.65 | 0.30 |
40 | 71 | 67 | 2.14 | 0.43 | |||
46 | 62 | 74 | 2.39 | 0.51 | |||
0.5 | 0.681 | 0.049 | 33 | 90 | 43 | 1.57 | 0.26 |
41 | 78 | 56 | 1.79 | 0.39 | |||
47 | 72 | 70 | 2.37 | 0.40 | |||
1 | 0.652 | 0.078 | |||||
3 | 0.621 | 0.151 |
- Citation: Andersson E, Axelsson J, Eckerwall G, Ansari D, Andersson R. Tissue factor in predicted severe acute pancreatitis. World J Gastroenterol 2010; 16(48): 6128-6134
- URL: https://www.wjgnet.com/1007-9327/full/v16/i48/6128.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i48.6128