Emodin enhances alveolar epithelial barrier function in rats with experimental acute pancreatitis

Table 1 Serum amylase level and pulmonary pathological scores in different groups (mean ± SD)

Group	Amylase (U/mL)	Edema (wet/dry)	Pathological score
Sham	3.5 ± 0.4	1.7 ± 0.2	0.3 ± 0.1
Pancreatitis	13.8 ± 1.6a	6.4 ± 0.5a	7.4 ± 0.8a
Emodin	8.2 ± 1.1c	4.1 ± 0.6c	4.8 ± 0.7c

Six rats were studied in each experimental group.

^aP < 0.05 vs sham group;

^cP < 0.05 vs pancreatitis group.

Table 2 Pulmonary cytokines and MPO in different groups (mean ± SD)

Group	TNF-α (pg/mg protein)	IL-6 (pg/mg protein)	MPO (U/mg protein)
Sham	2.8 ± 0.3	25.8 ± 2.9	3.1 ± 0.3
Pancreatitis	34.1 ± 3.5a	114.4 ± 12.6a	25.8 ± 2.9a
Emodin	25.4 ± 2.4c	93.0 ± 9.8c	20.3 ± 1.9c

Six rats were studied in each experimental group.

^aP < 0.05 vs sham group;

^cP < 0.05 vs pancreatitis group. MPO: Myeloperoxidase; TNF: Tumor necrosis factor.