First endoscopic procedure for diagnosis and staging of mediastinal lymphadenopathy

Table 1 Baseline characteristics and diagnostic categories of study population n (%)

Variables	Sequential approach	Selective approach	P value
No. of patients	34	34
Male/female	24/10	25/9
Age (mean ± SD, yr)	64.7 ± 11.2	65.1 ± 12.7
Mass on CT	24	23
Right-sided/left-sided,	13/11	12/11
No. of patients undergoing
TBNA	34 (100)	22 (65)	< 0.001
TBNA and EUS-FNA	11 (32)	2 (6)	< 0.05
Diagnostic yield (%)
First procedure	62	71	0.6
TBNA	62	73	0.6
Overall	79	73	0.8
Diagnostic categories
Malignancy	26	28
NSCLC/SCLC	22/3	21/7
Benign tumor	8	6
Sarcoid/tuberculosis	2/2	1/1

CT: Computed tomography; TBNA: Transbronchial needle aspiration; NSCLC: Non-small cell lung cancer; EUS-FNA: Endoscopic ultrasound-guided fine-needle aspiration.