Single-center experience of 309 consecutive patients with obscure gastrointestinal bleeding

Table 1 Baseline characteristics of patients with OGIB (n = 309)

Item	All (n = 309)	Massive bleeding (n = 49)	Chronic recurrent overt bleeding (n = 260)
Mean age ± SD (yr)	55.5 ± 16.6	52 ± 19.1	56.1 ± 16.1
Years (range, yr)	13-87	13-87	15-86
Gender n (%)	150 M (48.5)	27 M (55.1)	123 M (47.3)
	159 F (51.5)	22 F (44.9)	137 F (52.7)
Patient status (n)
Outpatient	141	0	141
Inpatient	168	49	119
Median units of RBCs transfused (U/mL)	4.63 ± 4.23	8.00 ± 6.46	4.00 ± 6.85
Mean Hb value (range, g/dL)	8.73 (4.52-12.10)	6.20 (4.52-9.85)	9.21 (6.56-12.10)

RBCs: Red blood cells; Hb: Hemoglobin; M: Male; F: Female.

Table 2 The yield of small bowel diagnostic findings on capsule endoscopy n (%)

	All (n = 309)	Massive bleeding (n = 49)	Chronic recurrent overt bleeding (n = 260)
Diagnostic	166 (53.7)	29 (59.2)	137 (52.7)
Non-diagnostic/negative	143 (46.3)	20 (40.8)	123 (47.3)

Table 3 CE diagnostic yields of massive bleeding and chronic recurrent bleeding n (%)

Type of lesion	All	Massive bleeding	Chronic recurrent overt bleeding
Angioectasias (Figure 2)	49 (28.3)	6 (22.2)	43 (29.9)
SB tumor	53 (30.6)	15 (51.7)	38 (26.0)
Mesenchymoma (Figure 3)	15 (8.7)	5 (17.2)	10 (6.9)
Polyps	13 (7.5)	2 (6.9)	11 (7.6)
Hemangioma (Figure 4)	6 (3.5)	2 (6.9)	4 (2.8)
Lipoma	4 (2.3)	0 (0)	4 (2.8)
Lymphoma (Figure 5)	4 (2.3)	2 (6.9)	2 (1.4)
BRBNS	2 (1.2)	2 (6.9)	0 (0)
Adenoma	1 (0.6)	1 (3.5)	0 (0)
Metastatic melanoma	1 (0.6)	0 (0)	1 (1.4)
Mass	7 (4.0)	1 (3.5)	6 (4.2)
Crohn’s disease (Figure 6)	25 (14.5)	2 (6.9)	23 (16.0)
Ulcer	15 (8.7)	2 (6.9)	13 (9.0)
Multiple ulcer	11 (6.4)	1 (3.5)	10 (7.6)
Isolated ulcer	4 (2.3)	1 (3.5)	3 (2.1)
SB verminosis	12 (6.9)	2 (6.9)	10 (6.9)
Non-specific enteritis	10 (5.8)	0 (0)	10 (6.9)
SB diverticulum	7 (4.0)	1 (3.5)	6 (4.2)
SAME	1 (0.6)	1 (3.5)	0 (0)
Portal hypertension SB disease	1 (0.6)	0 (0)	1 (1.4)
Total	173	29	144

SAME: Superior mesenteric artery embolus; SB: Small bowel; BRBNS: Blue rubber bleb nevus syndrome.