Effect of Lianshu preparation on lipopolysaccharide-induced diarrhea in rats

Table 1 Serum electrolyte levels in different groups (mean ± SD)

Group	Sodium (mmol/L)	Glucose (mmol/L)	Chlorine (mmol/L)	Kalium (mmol/L)
Normal	143.46 ± 3.34	8.37 ± 1.06	102.03 ± 2.82c	5.37 ± 0.96
LPS	102.48 ± 3.67b	4.99 ± 1.23b	98.40 ± 1.42a	3.38 ± 0.29b
LPS + Lianshu	140.35 ± 3.19d	8.49 ± 1.84d	106.29 ± 4.41bd	5.08 ± 0.66d
LPS + berberine	131.99 ± 4.86bdf	6.54 ± 2.30ae	102.5 ± 1.39de	4.32 ± 0.62bde

^aP < 0.05,

^bP < 0.01 vs normal group;

^cP < 0.05,

^dP < 0.01 vs LPS group;

^eP < 0.05,

^fP < 0.01 vs LPS + Lianshu group.

Table 2 Plasma NO and DAO levels in different groups (mean ± SD)

Group	No (&mgr;mol/L)	DAO (&mgr;mol/mL)
Normal	24.94 ± 3.38	0.82 ± 0.33
LPS	79.74 ± 7.39b	2.48 ± 0.42b
LPS + Lianshu	48.59 ± 4.70bd	1.43 ± 0.53bd
LPS + berberine	51.56 ± 8.38bdf	1.81 ± 0.42bde

^bP < 0.01 vs normal group;

^dP < 0.01 vs LPS group;

^eP < 0.05,

^fP < 0.01 vs LPS + Lianshu group.

Table 3 Number of IgA+ cells and SIgA in intestinal fluid of different groups (mean ± SD)

Group	IgA+ cells (/&mgr;m2)	SIgA (mg/L)
Normal	0.94 ± 0.21	0.50 ± 0.09
LPS	0.73 ± 0.22a	0.22 ± 0.66b
LPS + Lianshu	1.16 ± 0.19bd	0.59 ± 0.12d
LPS + berberine	1.09 ± 0.28ade	0.15 ± 0.19bce

^aP < 0.05,

^bP < 0.01 vs normal group;

^cP < 0.05,

^dP < 0.01 vs LPS group;

^eP < 0.05 vs LPS + Lianshu group.

Table 4 Counteractive effects of yeast on pyrexia in different groups (Δ°C) (mean ± SD)

Groups	1 h	2 h	3 h	4 h	5 h	6 h
Normal	0.58 ± 0.28	0.24 ± 0.71	0.20 ± 0.83	0.47 ± 0.30	0.17 ± 0.51	0.27 ± 0.65
Yeast	0.14 ± 0.94	0.75 ± 0.28b	1.06 ± 0.28b	1.16 ± 0.39b	1.69 ± 0.43b	1.46 ± 0.59b
Yeast + Lianshu	0.30 ± 0.38	0.58 ± 0.38	0.44 ± 0.56c	0.42 ± 0.29d	1.01 ± 0.43c	0.50 ± 0.44d
Yeast + acetaminophen	0.11 ± 0.73	0.21 ± 0.39c	0.37 ± 0.53c	0.66 ± 0.50d	0.74 ± 0.97ad	0.53 ± 0.98d

^aP < 0.05,

^bP < 0.01 vs normal group;

^cP < 0.05,

^dP < 0.01 vs yeast group.