Immunogenicity and immunoprotection of recombinant PEB1 in Campylobacter-jejuni-infected mice

Table 1 OD values of specific serum IgG antibody levels in BALB/c mice after immunization with recombinant PEB1 protein vaccine

Groups	Immune route	Serum IgG (mean ± SD)
Control	Subcutaneous	0.157 ± 0.010
P50 μg	Subcutaneous	0.365 ± 0.0191
P100 μg	Subcutaneous	0.521 ± 0.0241
P200 μg	Subcutaneous	0.619 ± 0.0281
Control	Muscular	0.157 ± 0.010
J50 μg	Muscular	0.350 ± 0.0161
J100 μg	Muscular	0.641 ± 0.0191
J200 μg	Muscular	0.638 ± 0.0231

¹P < 0.01 vs control group.

Table 2 Illness index of BALB/c mice after oral challenge with wild-type C. jejuni

Groups	Cases	Healthy	Sickness	Dead	Illness index	Protective rate (%)
Control	6	0	2	4	9.14 ± 0.90	0
J50 μg	6	2	1	3	5.71 ± 0.49	33.3
J100 μg	6	4	1	1	3.00 ± 0.82	75
J200 μg	6	3	2	1	3.14 ± 0.90	66.7