Continuous wound infusion of local anaesthetic agents following colorectal surgery: Systematic review and meta-analysis

Table 1 Results of meta-analyses

Outcome measure	Weighted mean difference	95% CI	P	Heterogeneity	Bias
Opioid consumption
Total	-40.13	-76.74 to -3.53	0.03	P = 0.02	P = 0.27
Postoperative day 1	-8.34	-16.38 to -0.31	0.04	P = 0.019	P = 0.48
Postoperative day 2	-9.41	-20.37 to 1.39	0.087	NA	NA
Postoperative day 3	-4.8	-11.72 to 2.13	0.17	NA	NA
Visual analogue pain score at rest
Postoperative day 1	-0.18	-1.31 to 0.95	0.75	P < 0.05	P = 0.80
Postoperative day 2	-0.20	-1.06 to 0.66	0.65	P < 0.05	P = 0.47
Postoperative day 3	-0.43	-0.81 to -0.044	0.029	NA	P = 0.63
Visual analogue pain score on coughing or movement
Postoperative day 1	-1.14	-2.24 to -0.041	0.04	NA	NA
Postoperative day 2	-0.97	-1.91 to -0.029	0.04	NA	NA
Postoperative day 3	-0.61	1.01 to -0.20	0.0038	NA	NA
Duration of hospital stay	-20.87	-46.94 to 5.21	0.12	P = 0.016	P = 0.30
Time to return of bowel function	-9.4	-33.98 to 15.17	0.45	NA	NA