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Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Jun 21, 2008; 14(23): 3754-3758
Published online Jun 21, 2008. doi: 10.3748/wjg.14.3754
Table 1 Effect of FHIT gene on cell growth and apoptosis in human hepatocellular carcinoma (mean ± SD)
Cell typeG0/G1SG2/MApoptosis rate (%)
Hep3B54.36 ± 0.7817.40 ± 1.3228.01 ± 1.123.78 ± 0.36
Hep3B-C53.17 ± 0.5218.23 ± 2.5128.55 ± 0.553.52 ± 0.33
Hep3B-FHITa72.23 ± 0.8412.57 ± 0.4215.12 ± 1.319.74 ± 0.43
Table 2 Mean tumor formation time and mean tumor weight in nude mice implanted with Hep3B, Hep3B-C or Hep3B-FHIT cells ( n = 5, mean ± SD)
GroupMean tumor formation time (d)Mean tumor weight (g)
Hep3B/nude3.22 ± 0.313.66 ± 0.40
Hep3B-C/nude3.08 ± 0.343.94 ± 0.39
Hep3B-FHIT/nude12.17 ± 1.190.60 ± 0.04
Total F value72.38168.36
Total P value0.000.00