Editorial
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Apr 7, 2008; 14(13): 1972-1980
Published online Apr 7, 2008. doi: 10.3748/wjg.14.1972
Table 1 IBD immunopathogenesis
Immune dysregulation
Cytokines
Epiteliol barrier function
Oral tolerance
Reactive oxygen species (ROS)
Antioxidant defence system
Table 2 Medical management based on pathogenesis
Dietary nutrients
Polyunsaturated fatty acids (PUFAs)
Fiber
Probiotics
Prebiotics
Flavonoids
Antagonist platelet-activating factor (PAFs)
Biological therapies
Anti-inflammatory/Immunosuppressive
Immunomodulators
Generation regulatory T cells/Activation effector T cells
Inhibition of recruitment, migration, adhesion molecules
Epithelial repair/Restitution barrier function
Induction apoptosis
Autologous hematopoietic stem cell transplant