Insulin resistance in H pylori infection and its association with oxidative stress

Table 1 Demographic and clinical data of H pylori positive and negative groups (mean ± SD)

Parameters	H pylori negative	H pylori positive
	(n = 48)	(n = 55)	P
Age (yr)	35 ± 15	37 ± 12	NS
Sex (Female/Male)	28/20	29/26	NS
Body mass index (kg/m2)	22.5 ± 3.1	23.5 ± 1.6	NS
Glucose (mg/dL)	98.15 ± 14.97	97.71 ± 14.39	NS
Insulin (μU/mL)	3.61 ± 1.67	6.92 ± 3.86	< 0.001
HOMA-IR	0.89 ± 0.47	1.67 ± 0.99	< 0.001

IR: Insulin resistance; NS: Not significant.

Table 2 Oxidative and antioxidative parameters in H pylori positive and negative groups (mean ± SD)

	H pylori negative(n = 48)	H pylori positive(n = 55)	P
TAC (mmol Trolox eq./L)	1.70 ± 0.50	1.36 ± 0.33	< 0.001
TOS (μmol H2O2 equiv./L)	5.08 ± 0.95	6.79 ± 3.40	< 0.001
OSI (arbitrary unit)	3.10 ± 0.92	5.42 ± 3.40	< 0.001

TAC: Total antioxidant capacity; TOS: Total oxidant status; OSI: Oxidative stress index.