H pylori infection and reflux oesophagitis: A case-control study

Table 1 Frequency of H pylori infection in two groups n (%)

Group	H pylori			Rut	DiagnosisH pylori	Total
	Cardia	Corpus	Antrum
Case	27 (52.9)	25 (49.0)	37 (72.5)	23 (45.1)	45 (88.2)	51 (100.0)
L.A. classification
A	11 (21.6)	8 (15.7)	12 (23.5)	9 (17.7)	16 (31.4)	17 (33.3)
B	11 (21.6)	11 (21.6)	17 (33.4)	12 (23.5)	21 (41.2)	24 (47.1)
C	4 (7.8)	5 (9.8)	7 (13.7)	2 (3.9)	7 (13.7)	9 (17.7)
D	1 (1.9)	1 (1.9)	1 (1.9)	0	1 (1.9)	1 (1.9)
Control	28 (57.1)	27 (55.1)	31 (63.3)	22 (44.9)	38 (77.6)	49 (100.0)
Total	55 (55.0)	52 (52.0)	68 (68.0)	45 (45.0)	83 (83.0)	100 (100.0)

Table 2 Different histological findings in two groups n (%)

Histological finding	Case	Control	Total	OR (95% CI)
H pylori infection1	45 (88.2)	38 (77.6)	83 (83.0)	2.2 (0.7-7.4)
Chronic inflammation in cardia	14 (27.5)	18 (36.7)	32 (32.0)	0.7 (0.3-1.7)
Chronic inflammation in corpus	8 (15.7)	22 (44.9)	30 (30.0)	0.2 (0.1-0.6)
Chronic inflammation in antrum	28 (54.9)	30 (61.2)	58 (58.0)	0.8 (0.3-1.8)
Overall gastritis categorization (Sydney classification)
Diffuse chronic active gastritis	15 (29.4)	26 (53.1)	41 (42.0)	0.4 (0.2-0.9)
Cardia predominant chronic active gastritis	1 (2.0)	1 (2.0)	2 (2.0)	0.9 (0.0-36.3)
Corpus predominant chronic active gastritis	0	1 (2.0)	1 (1.0)	0.0 (0.0-16.9)
Antrum predominant chronic active gastritis	3 (5.9)	5 (10.2)	8 (8.0)	0.6 (0.1-2.9)
Multifocal metaplastic or atrophic gastritis	1 (2.0)	1 (2.0)	2 (2.0)	0.9 (0.0-36.3)
Chronic carditis	1 (2.0)	2 (4.1)	3 (3.0)	0.5 (0.0-6.9)
Diffuse chronic gastritis	10 (19.6)	2 (4.1)	12 (12.0)	5.7 (1.1-40.4)
Normal	20 (39.2)	11 (22.4)	31 (31.0)	2.2 (0.9-5.8)
Total	51 (100.0)	49 (100.0)	100 (100.0)	-

¹Based on histology and rapid urease test.

Table 3 Scores of inflammation, activity, and gastritis in two groups

Group	Cardia	Corpus	Antrum	P
		Median (range)
Case
H pylori n (%)	27 (52.9)	25 (49.0)	37 (72.5)	0.0051
Activity score	0 (0-2)	0 (0-2)	0 (0-3)	0.0572
Inflammation score	1 (0-2)	1 (0-2)	2 (0-3)	0.0002
Gastritis score	0 (0-4)	1 (0-4)	2 (0-6)	0.0002
Control
H pylori n (%)	28 (57.1)	27 (55.1)	31 (63.3)	0.4651
Activity score	1 (0-2)	1 (0-3)	1 (0-3)	0.0002
Inflammation score	1 (0-3)	1 (0-3)	2 (0-3)	0.0002
Gastritis score	2 (0-5)	2 (0-6)	3 (0-6)	0.0002

¹Cochran’s Q test;

²Friedman test.