Editorial
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 28, 2006; 12(32): 5108-5112
Published online Aug 28, 2006. doi: 10.3748/wjg.v12.i32.5108
Table 1 Frequency of lymph node metastases in early gastric cancer[20]
CriteriaFrequency (No. with metastasis/total number)95% CI
Intramucosal cancer differentiated adenocarcinoma, no lymphatic vascular invasion, irrespective of ulcer findings, tumor ≤ 3 cm0/12300-0.3%
Intramucosal cancer differentiated adenocarcinoma, no lymphatic vascular invasion, without ulcer findings, irrespective of tumor size0/9290-0.4%
Intramucosal cancer undifferentiated adenocarcinoma, no lymphatic vascular invasion, without ulcer findings, tumor ≤ 2 cm0/1410-2.6%
Cancer with minute submucosal penetration (≤ 500 μm) differentiated adenocarcinoma, no lymphatic vascular invasion, irrespective of ulcer findings, tumor ≤ 3 cm0/1450-2.5%
Table 2 Outcomes of ESD
TechniquesEn bloc resection rate %Local recurrent rate %Complication rate %
20 mm> 21 mmBleedingPerforation
ESD with IT knife[42]95 (686/719)86 (271/314)NA6 (59/945)4 (35/945)
ESD with the tip of an electrosurgical snare (thin type)/a flex knife[8]95 (56/59)NA1.7 (1/59)3.4 (2/59)
ESD with sodium hyaluronate and small-caliber-tip transparent hood[43]100 (37/37)97 (32/33)NA1 (1/70)0 (0/70)
ESD with a hook knife[44]95 (194/204)0.5 (1/204)NA1.5 (3/204)
Submucosal-endoscopic resection with hypertonic saline-epinephrine solution (S-ERHSE)[45]NA79 (36/46)0 (0/46)4(2/46)8 (4/46)
ESD with a mixture of high-molecular-weight hyaluronic acid and Glyceol[35]100 (26/26)0 (0/26)3.8 (1/26)0 (0/26)
ESD with TT knife[28]88 (14/16)NANA0 (0/16)