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Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 14, 2006; 12(30): 4813-4818
Published online Aug 14, 2006. doi: 10.3748/wjg.v12.i30.4813
Table 1 Prevalence data according to population and methodology of the study
Author (year ofpublication)Population characteristicsDiagnostic assayStudy typePrevalence
Criscuoli (2004)42 pts with severe colitisHE-ICH on rectal biopsy + antigenemia pp65prospective21%
Kishore (2004)63 pts with severe colitis (36 steroid resistant)Serology-HE and qualitative PCRprospective16% 22%
Wada (2003)47 pts with severe colitisAntigenemiaprospective34%
de Saussure (2004)64 pts with active colitisSerology-viremia-antigenemia- HE-ICHprospective1.5%-6%
Vega (1999)267 active colitisHE-ICHretrospective3%
Pofelski (2005)48 pts severe colitisQuantitative PCR on colonic biopsiesretrospective/ prospective38% 60%
Kambham (2004)40 pts steroid resistant (25 operated on for colectomy)HE-ICHretrospectiveOverall 25% Operated on pts 24%
Papadakis (2001)1895 steroid resistant ptsHEretrospective0.5%
Cottone (2001)19 Steroid resistant ptsHE-ICH on rectal biopsy + antigenemia pp65prospective36%
Maconi (2005)77 pts operated on for colectomyHE-ICH on surgical specimenprospective22% overall 27% steroid resistant
Takahashi (2004)69 surgical specimen of IBD ptsHE-ICH on biopsy and surgical specimenretrospective11.5%
Alcalà (2000)39 pts operated on for colectomyHE + ICHretrospective18%
Eire-Brook (1986)26 pts operated on for colectomyLight and electron microscopy- ICHretrospective11.5%
Cooper (1977)46 pts operated on for colectomyHEretrospective13%
Rahbar (2003)23 pts with IBD (13 UC-10 CD)ICH+ in situ hybridizationprospective92/100%
Wakefield (1992)50 pts with IBD (29 CD-21 UC)qualitative PCRprospective66/81%