Role of Kupffer cells in acute hemorrhagic necrotizing pancreatitis-associated lung injury of rats

Table 1 Serum amylase in all experimental groups (U/L, mean±SD)

Group	Serum amylase
	3 h(n=6)	6 h(n=6)
Sham	499.4 ± 86.3	503.8 ± 91.2
AHNP	10 444.5 ± 1 863.2b	13 316.4 ± 1 374.1b
GdCl3 pretreatment	9 107.1 ± 569.9b	12 420.4 ± 1 779.2b

^bP<0.001 vs sham group.

Table 2 Influence of GdCl₃ on hepatic functions of experimental animals (U/L, mean±SD)

Group	n	Serum AST	Serum ALT
Sham 3 h	6	74.2 ± 13.6	31.6 ± 9.3
Sham 6 h	6	71.3 ± 15.0	32.7 ± 11.3
GdCl3 control	6	82.5 ± 14.6	28.9 ± 8.7

Table 3 Serum TNF-α and IL-1 in all experimental groups (mean±SD)

Group	n	TNF-α (pg/mL)	IL-1 (μg/L)
3 h
Sham	6	32.0 ± 8.6	0.29 ± 0.08
AHNP	6	113.9 ± 18.5	0.81 ± 0.11
GdCl3 pretreatment	6	71.1 ± 14.3b	0.49 ± 0.12b
6 h
Sham	6	31.9 ± 8.2	0.28 ± 0.07
AHNP	6	126.3 ± 12.6	0.91 ± 0.12
GdCl3 pretreatment	6	78.0 ± 17.2b	0.53 ± 0.13b

^bP<0.01 vs AHNP group.

Table 4 Lung tissue MPO level in all groups (mU/mg prot, mean±SD)

Group	MPO
	3 h(n = 6)	6 h(n = 6)
Sham	0.51 ± 0.13	0.50 ± 0.17
AHNP	1.59 ± 0.26	1.79 ± 0.23
GdCl3 pretreatment	0.94 ± 0.15b	1.02 ± 0.19b

^bP<0.01 vs AHNP group

Table 5 Histopathologic scores of lung tissue in all groups (mean±SD)

Group	Lung histopathologic scores
	3 h(n = 6)	6 h(n = 6)
Sham	0.17±0.04	0.17±0.04
AHNP	2.50±0.55b	2.67±0.52b
GdCl3 pretreatment	1.87±0.41a	2.00±0.38a

^aP<0.05 vs AHNP group;

^bP<0.01 vs sham operation group.