Hyperlipidemia intensifies cerulein-induced acute pancreatitis associated with activation of protein kinase C in rats

Table 1 Effects of caerulein and albumin therapy on histological pancreatic lesions, volume of ascites and ratio of pancreatic wet/dry weight (mean±SD)

Group	Time	Histological score	Ascites(ml)	Wet/dry
C(sal)	3 h	0.33 ± 0.52	0	1.35 ± 0.09
	6 h	0.33 ± 0.52	0	1.35 ± 0.09
AP	3 h	3.50 ± 1.38a	0.87 ± 0.58	1.67 ± 0.05a
	6 h	5.33 ± 1.03a	1.58 ± 0.92	1.76 ± 0.14a
HAP	3 h	5.17 ± 1.17c	2.08 ± 0.58c	1.95 ± 0.44
	6 h	6.83 ± 1.16c	4.12 ± 1.58c	2.15 ±0.39
THAP	3 h	4.83 ± 1.16	1.87 ± 0.93	1.72 ± 0.14
	6 h	6.67 ± 1.21	3.68 ± 1.42	1.88 ± 0.33

^aP < 0.05 vs control group,

^cP <0 .05 vs caerulein group.

Table 2 Effects of albumin therapy on serum TG, TCH and AMY in rats (mean±SD)

Group	Time	TG	TCH	AMY
C(sal)	-	47.00 ± 23.38	26.25 ± 2.36	1658.50 ± 335.21
AP	3 h	63.66 ± 11.52	61.00 ± 6.00	5128.66 ± 259.65
	6 h	72.66 ± 22.65	67.00 ± 8.71	6641.00 ± 213.75
C(tri)	3 h	899.51 ± 240.52	76.03 ± 16.14	1652.55 ± 300.46
	6 h	797.07 ± 356.18	60.51 ± 33.49	1253.72 ± 254.80
HAP	3 h	1604.16 ± 248.10a	264.33 ± 50.33a	18390.00 ± 7158.77a
	6 h	1506.66 ± 327.72c	230.33 ± 31.87c	11611.66 ± 4513.67c
THAP	3 h	1396.83 ± 658.65	221.00 ± 60.46	20473.33 ± 12005.46
	6 h	1167.33 ± 228.28	211.00 ± 14.02	16524.39 ± 5273.52

^aP < 0.05,

^cP < 0.05 vs triton group.