L-arginine administration ameliorates serum and pulmonary cytokine response after gut ischemia-reperfusion in immature rats

Table 1 Effects of L-arg on ET-1, MDA, NO, and TNFα levels in serum.

Group	n	ET-1 (pg/mL)	MDA (nmol/L)	NO (mmol/L)	TNFα(ng/mL)
SHAM	6	226.01±37.91	23.78±7.81	108.17±56.28	3.20±0.39
IR	7	229.68±68.20	25.54±9.32	87.57±23.17	2.66±0.54
IR+L-arg	6	246.50±31.44	8.93±1.50b	162.17±42.93d	3.76±0.95

^bP<0.01 vs either SHAM or IR group;

^dP<0.01 vs IR group.

Table 2 Effects of L-arg on ET-1, MDA, NO, and TNFα levels in lung homogenates.

Groups	n	ET-1 (pg/mL)	MDA (nmol/L)	NO (mmol/L)	TNFα(ng/mL)
SHAM	6	35.52±10.82a	16.62±2.28b	8.12±3.20	1.24±0.19
IR	7	50.83±22.05b	21.90±4.82b	4.97±0.05	1.07±0.17
IR+L-arg	6	13.81±7.84	10.73±1.99	4.98±0.82	0.91±0.33

^aP<0.05 vs IR+L-arg group;

^bP<0.01 vs IR+L-arg group.