Excessive portal flow causes graft failure in extremely small-for-size liver transplantation in pigs

Table 1 Graft characteristics (mean±SD)

Parameters	Group without PCS	Group with PCS
	(n = 11)	(n = 11)
DBW (kg)	21.8±2.7	20.8±1.1
RBW (kg)	22.8±1.2	22.1±2.6
GW (g)	131.8±18.3	139.3±32.0
RLW (g)	525.4±41.4	548.3±63.8
GWRLW (%)	25.1±2.7	25.4±3.4
GWBW (%)	0.58±0.09	0.63±0.13
Anhepatic time (min)	43±2	41±4
Operation time (min)	261±28	263±44
Total ischemic time (min)	151±51	161±20

DBW: donor body weight; RBW: recipient body weight; GW: liver graft weight at implantation; RLW: recipient native liver weight; GWRLW: percentage of GW to the recipient native liver weight; GWBW: percentage of GW to the recipient body weight.

Table 2 Changes of hepatic hemodynamics (mean±SD)

Parameters	Group	At laparotomy	After transplantation
Portal flow	Group without PCS	118.2±26.9	270.5±72.9b,a
(mL/min/100 g liver tissue)	Group with PCS	124.2±27.8	42.7±32.3a
Hepatic arterial flow	Group without PCS	50.1±8.3	37.7±21.0a
(mL/min/100 g liver tissue)	Group with PCS	50.5±11.6	75.1±39.5
Total liver blood flow	Group without PCS	168.3±30.9	308.2±52.8b,a
(mL/min/100 g liver tissue)	Group with PCS	174.8±29.1	117.8±42.1c
Ratio of PF/TLBF (%)	Group without PCS	70.2±4.2	87.8±8.2b,a
	Group with PCS	71.1±4.9	36.3±19.5a

PF: portal flow; TLBF: total liver blood flow. bP<0.01 vs the group with PCS; aP<0.01 vs at laparotomy; aP<0.05 vs the group with PCS; cP<0.05 vs at laparotomy.