Brief Reports
Copyright ©The Author(s) 2005.
World J Gastroenterol. Sep 28, 2005; 11(36): 5696-5700
Published online Sep 28, 2005. doi: 10.3748/wjg.v11.i36.5696
Table 1 Characteristics of patients (mean±SD, n)
ParametersValues
Sex (male/female)Mar-33
Age (range)63.3±9.2 (42-78 yr)
Histopathology
Well-differentiated6
Moderately differentiated23
Poorly differentiated7
Stage (UICC)
I4
II7
III18
IVa7
Table 2 Relation between immunohistochemical expressions of biological markers and response of esophageal squamous cell car-cinoma to CRT (n)
MarkersResponderNon-responderP
(CR+PR)(NC+PD)
p53(-)1410.0095
p53(+)1110
MT (-)2150.019
MT (+)46
CDC25B (-)780.0129
CDC25B (+)183
Table 3 Relation between expressions of biological markers and response of esophageal squamous cell carcinoma to CRT (n)
MarkersResponderNon-responderP
(CR+PR)(NC+PD)
Bax (-)1780.799
Bax (+)830.799
Bcl-2 (-)1880.836
Bcl-2 (+)730.836
Cyclin D1 (-)1560.305
Cyclin D1 (+)1050.305
VEGF (-)1050.936
VEGF (+)1560.936
Ki67 (-)410.586
Ki67 (+)21100.586
Table 4 Relation between effects of CRT and immunohistochemical staining
Immunoreactivity/responseP
p53--++0.027
CDC25B+-+-
Responder9592
Non-responder0137
MT--++
0.0305
CDC25B+-+-
Responder16522
Non-responder2315