Expression of cell cycle regulator p57kip2, cyclinE protein and proliferating cell nuclear antigen in human pancreatic cancer: An immunohistochemical study

Table 1 Expression of p57^kip2 protein in pancreatic cancer tissues

	p57kip2 protein expression
Characteristics	-	+	++	+++	Rate (%)
Tumor tissue	17	11	3	1	46.9a
Well-differentiated	7	9	2	1	63.2c
Moderately or
poorly-differentiated	10	2	1	0	23.1c
Lymph node metastasis	9	2	1	0	25.0e
Non-lymph node
metastasis	8	9	2	1	60.0e
Adjacent tissue	8	13	6	5	75.0a

^aP<0.05,

^cP<0.05,

^eP>0.05 vs others.

Table 2 Expression of cyclinE protein in pancreatic cancer tissues

Characteristics	CyclinE protein expression
	-	+	++	+++	Rate (%)
Tumor tissue	10	7	9	6	68.8a
Well-differentiated	9	5	4	1	52.6c
Moderately or
poorly-differentiated	1	1	6	5	84.6c
Lymph node metastasis	1	1	5	5	91.7e
Non-lymph node
metastasis	9	6	4	1	55.0e
Adjacent tissue	18	6	8	0	43.8a

^aP<0.05,

^cP<0.05,

^eP<0.05 vs others.

Table 3 Expression of PCNA in pancreatic cancer tissues

Characteristics	PCNA protein expression
	-	+	Rate (%)
Tumor tissue	9	23	71.9a
Well-differentiated	8	11	57.9c
Moderately or poorly-differentiated	1	12	92.3c
Lymph node metastasis	0	12	100e
Non-lymph node metastasis	9	11	55.0e
Adjacent tissue	18	14	43.8a

^aP<0.05,

^cP<0.05,

^eP<0.05 vs others.

Table 4 Relationship between expression of p57^kip2 and cyclinE proteins

p57kip2	CyclinE protein expression
	-	+	++	+++	Rate (%)
–	4	4	6	3	76.5
+	4	3	2	2
++	2	0	0	1	60.0
+++	0	0	1	0