Brief Reports
Copyright ©The Author(s) 2005.
World J Gastroenterol. Aug 21, 2005; 11(31): 4886-4890
Published online Aug 21, 2005. doi: 10.3748/wjg.v11.i31.4886
Table 1 ICAM-1 genotypic and allele distribution in BA patients and controls
BA patients, n (%) n = 83Controls, n (%) n = 115Odds ratio (95% CI)P
Age (yr)6.09±4.6713.07±2.13<0.0005
Male37:46:0057:58:000.49
Genotype
E/E28 (33.74)41 (35.65)0.92 (0.51–1.66)0.78
E/K7 (8.43)11 (9.57)0.87 (0.32–2.35)0.78
K/K48 (57.83)63 (54.78)1.13 (0.64–2.00)0.67
Alleles
E63 (37.95)93 (40.43)0.90 (0.60–1.36)0.62
K103 (62.05)137 (59.57)1.11 (0.74–1.67)
E/K ratio0.610.68
Table 2 Demographic data, liver function test, and serum sICAM-1 levels between BA patients without jaundice and with persistent jaundice (mean±SD)
BA patientsNo jaundice (n = 41)Persistent jaundice (n = 31)P
Age (yr)6.41±4.056.00±5.910.73
Male:female22:1911:200.12
Albumin (g/dL)4.41±0.563.71±0.83<0.0005
Total bilirubin (mg%)0.79±0.4412.04±10.53<0.0005
DB (mg%)0.24±0.269.36±7.85<0.0005
AST (IU/L)84.12±67.28228.26±130.45<0.0005
ALT (IU/L)96.93±93.83161.84±97.930.006
AP (IU/L)380.90±249.80593.20±293.490.002
GGT (IU/L)163.16±175.49384.65±404.720.004
sICAM-1 (<3 500:≥3 500 ng/mL)37:04:0011:20<0.0005
Table 3 ICAM-1 genotypic and allele distribution in BA patients without jaundice and with persistent jaundice
No jaundice, n (%) n = 34Jaundice, n (%) n = 29Odds ratio (95%CI)P
Age (yr)5.91±3.925.66±5.170.84
Male18:1611:180.23
Genotype
E/E9 (26.47)10 (34.48)0.68 (0.23-2.01)0.49
E/K3 (8.82)3 (10.34)0.83 (0.15-4.52)0.84
K/K22 (64.71)16 (55.18)1.49 (0.52-4.11)0.44
Alleles
E21 (30.88)23 (39.66)0.68 (0.32-1.42)0.3
K47 (69.12)35 (60.34)1.47 (0.70-3.07)
E/K ratio0.450.66