Overexpression of S100A4 is closely associated with progression of colorectal cancer

Table 1 Relationship between expression of S100A4 and tumor stage of colorectal carcinoma

	Cytoplasm		Positive (%)	P	Nuclear		Positive (%)	P
	+	-			+	-
Stage				0.00011				<0.052
A	4	9	30.8		1	12	7.7
B	21	26	44.6		7	40	14.9
C	37	19	66.1		12	44	21.4
D	7	1	87.5		4	4	50
L/N metastasis				0.02553				0.51843
+	39	20	66.1		10	49	16.9
-	30	35	46.1		14	51	21.5
Site				0.51543				0.27193
Right	12	14	46.2		7	19	26.9
Left	57	41	53.4		17	81	17.3
Tumor size				0.64213				1.00003
<5 cm	33	24	57.9		11	46	19.2
≥5 cm	36	31	53.7		13	54	19.4
Survival period				0.77193				0.95633
<24 mo	6	4	60		2	8	20
≥24 mo	63	51	55.3		22	92	19.3
Total	69	55			24	100

¹Cochran’s linear trend test;

²Bartholomew test; ³χ² test.