In vivo and in situ detection of colorectal cancer using Fourier transform infrared spectroscopy

Table 1 Results of FTIR spectral analysis and corresponding pathological detection of measured colorectal tissues.

Case number	Tissue	Sex	Age (yr)	Measurement date	FTIR measurement mode	Characteristics of FTIR spectra	FTIR analysis results	Pathological results
						The bands of C-H stretching
1	Cecum	F	69	2000-7-21	in vivo during	vibration and C = O vibration		Adenocarcinoma
					surgical operation	disappeared; peak position of	Cecum cancer	of cecum
						amide I = 1641/cm; Iamide II (middle
						weak); I1393/cm>I1460/cm
						I2969/cm (weak) , I2934/cm		Moderately
2	Sigmoid colon	M	63	2003-7-22	in vivo during	(weak); peak position of	Colon cancer	differentiated
					surgical operation	amide I = 1636/cm; Iamide II		adenocarcinoma of
						(very weak); I1391 /cm>I1460/cm		sigmoid colon
						I2989/cm (weak) , I2924/cm
3	Sigmoid colon	M	52	2003-11-3	in vivo during	(weak); peak position of	Colon cancer	Carcinoma
					surgical operation	amide I = 1640/cm; Iamide II		of sigmoid
						(very weak); I1413/cm>≈I1456/cm
						The bands of C-H stretching
4	Transverse colon M		77	2003-12-5	in vivo during	vibration and C = O vibration	Colon cancer	Adenocarcinoma
					surgical operation	disappear; peak position of amide		of transverse colon
						I = 1638/cm; Iamide II (very weak);
						I1400/cm>I1446/cm
						I2924/cm (weak), I2850/cm (weak),		Moderately
5	Rectum	M	60	2003-7-22	in vivo before	I1731 cm-1 (weak); peak position of	Rectum cancer	differentiated
					surgical operation	amideI = 1641/cm; Iamide II (weak);		adenocarcinoma
						I1402 /cm>I1469/cm		of rectum