HMLH1 gene mutation in gastric cancer patients and their kindred

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May 28, 2005 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2005; 11(20): 3144-3146
Published online May 28, 2005. doi: 10.3748/wjg.v11.i20.3144

Table 1 Comparison of hMLH1mutation among the gastric cancer kindreds, sporadic gastric cancer patients, and control individuals.

Groups	Cases	HMLH1 mutation		Mutation rate (%)
Groups	Cases	Exon 8	exon 12	Mutation rate (%)
Probands of kindreds	16	2	2	25^b
Non-cancerous members of kindreds	104	12	7	18^d
Sporadic gastric cancer patients	56	2	2	7
Control individuals	100	2	3	5

^bP＜0.01 χ² = 7.71,

^dP＜0.01 χ² = 8.65 vs control individuals.

Citation: Li JH, Shi XZ, Lü S, Liu M, Cui WM, Liu LN, Jiang J, Xu GW. HMLH1 gene mutation in gastric cancer patients and their kindred. World J Gastroenterol 2005; 11(20): 3144-3146
URL: https://www.wjgnet.com/1007-9327/full/v11/i20/3144.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i20.3144