Expression of cellular FLICE-inhibitory protein and its association with p53 mutation in colon cancer

Table 1 Expression of c-FLIP gene in colon cancer and matched normal tissues (mean±SD).

Group	Number	c-FLIP protein	P	c-FLIP mRNA	P
Normal tissue	45	5.21±0.86		0.38±0.10
Cancer tissue	45	7.04±1.20	<0.01	0.63±0.12	<0.01

Table 2 Correlation between c-FLIP mRNA and protein and p53 mutation in colon cancer (mean±SD).

Group	Number	c-FLIP protein	P	c-FLIP mRNA	P
p53 positive	27	7.57±1.30		0.59±0.13
p53 negative	18	6.25±1.27	<0.01	0.69±0.14	<0.01