Brief Reports
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Mar 28, 2005; 11(12): 1867-1871
Published online Mar 28, 2005. doi: 10.3748/wjg.v11.i12.1867
Table 1 Select characteristics of cardia cancer cases (n = 159) and controls (n = 192).
VariableCases
Controls
P
n(%)n(%)
Age (yr)
≤596239.09348.4
60-696138.46031.3
≥703622.63920.30.196
Sex
Female3018.95227.1
Male12981.114072.90.07
Education (yr)
<129559.78946.4
≥126440.310353.60.012
Table 2 Association of CYP2E1 polymorphisms with cardia cancer risk.
CYP2E1Cases
Controls
OR (95%CI)1
N%N%
C1/c25735.811057.31
C2/c263.852.6
C1/c19660.47740.12.37 (1.52-3.70)
Table 3 Associations of cardia cancer risk with joint distribution of CYP2E1 genotypes and smoking status.
Smoking statusCYP2E1Cases
Controls
OR (95%CI)1OR (95%CI)2
n%n%
Smoking
Neverc1/c2 or c2/c23320.755528.6511
EverC1/c13522.015327.601.05 (0.561.99)1.03 (0.522.06)
Everc1/c2 or c2/c23018.876031.250.85 (0.401.78)0.91 (0.392.14)
EverC1/c16138.362412.504.68 (2.1910.04)3.94 (1.609.67)
Daily consumed cigarettes
1-19c1/c2 or c2/c285.03157.810.81 (0.272.39)0.62 (0.182.16)
1-19C1/c195.6663.132.99 (0.8810.19)2.59 (0.5412.45)
≥20c1/c2 or c2/c22213.844523.440.90 (0.411.98)1.04 (0.412.67)
≥20C1/c15232.70189.385.34 (2.3811.95)4.17 (1.6310.63)
Smoking duration (yr)
1-29c1/c2 or c2/c2106.292513.020.71 (0.271.87)0.82 (0.272.49)
1-29C1/c11911.95189.382.10 (0.855.21)1.99 (0.616.49)
≥30c1/c2 or c2/c22012.583518.231.10 (0.472.57)1.00 (0.372.69)
≥30C1/c14226.4263.1313.32 (4.5039.45)8.44 (2.5827.59)