Age scope of high-risk population for esophageal cancer in Ci county

Table 1 Age distribution of MEED, PL and EC detected by cytological screening of 16763 persons.

Histology Grade	Age						Total
	40 yr	45 yr	50 yr	55 yr	60 yr	65 yr
Normal (case, %)	2718 (50.6)	1518 (43.8)	1094 (39.1)	945 (35.6)	651 (29.5)	95 (30.7)	7021
MEED	1574 (29.3)	1100 (31.7)	928 (33.1)	882 (33.2)	758 (34.9)	104 (33.1)	5346
PL	1056 (19.7)	816 (23.6)	745 (26.6)	782 (29.5)	720 (33.2)	98 (31.7)	4217
EC	20 (0.4)	29 (0.8)	31 (1.1)	46 (1.7)	41 (1.9)	12 (3.9)	179
Total	5368	3463	2798	2655	2170	309	16763

MEED: mild esophageal epithelia dysplasia, PL: precancerous lesion, EC: EC.

Table 2 Age distribution by endoscopic pathologic screening of 2013 persons.

Pathology Grade	Age						Total
	40 yr	45 yr	50 yr	55 yr	60 yr	65 yr
Normal (case, %)	746 (94.2)	388 (84.7)	239 (74.2)	165 (73.3)	83 (55.7)	33 (49.3)	1654
PL	43 (5.4)	57 (12.4)	67 (20.8)	39 (17.3)	47 (31.5)	17 (25.4)	270
Early cancer	3 (0.4)	10 (2.2)	11 (3.4)	14 (6.2)	11 (7.4)	8 (11.9)	57
Advanced cancer	0 (0.0)	3 (0.7)	5 (1.6)	7 (3.1)	8 (5.4)	9 (13.4)	32
Total	792	458	322	225	149	67	2013

PL: precancerous lesion.

Table 3 Ridit value by histology by age distribution in comparison with standard group.

Age (yr)	Cases	Ridit Value	95%CI
451	3463	0.5
40	5368	0.46	(0.45-0.47)
50	2798	0.53	(0.51-0.54)
55	2655	0.55	(0.54-0.56)
60	2170	0.58	(0.57-0.59)
65	309	0.59	(0.55-0.62)
Total	16763

¹Standard group.

Table 4 Ridit value for endoscopic pathology by age distribution in comparison with standard group.

Age (yr)	Cases	Ridit Value	95%CI
451	458	0.5
40	792	0.45	(0.43-0.47)
50	322	0.55	(0.52-0.58)
55	225	0.56	(0.52-0.60)
60	149	0.65	(0.60-0.70)
65	67	0.69	(0.62-0.76)
Total	2013

¹Standard group.

Table 5 Average age of each histology grade by cytology screening.

Histology grade	Cases	Mean±SD	t value	P
MEED	5346	50.3±7.56	7.162	<0.001
SEEDI	3179	51.2±7.70	3.554	<0.001
SEED II	866	51.6±7.54	4.537	<0.001
NEC	172	52.4±7.14	5.527	<0.001
EC	179	54.4±7.23

Table 6 Average age of each pathology grade by endoscopic screening and tumor registration.

Pathology grade	Cases	Mean±SD	t value	P
Mild dysplasia	172	51.6±7.90	5.250	<0.001
Moderate dysplasia	157	53.5±7.42	4.22	<0.001
Severe dysplasia	53	51.4±7.26	4.764	<0.001
Early cancer	50	55.6±7.31	2.248	<0.05
Advanced cancer1	9265	61.7±11.23	1.086	>0.05
Advanced cancer	31	56.7±6.76

¹From tumor registration.