Concentrations of α- and β-defensins in gastric juice of patients with various gastroduodenal diseases

Table 1 Plasma human neutrophil peptides 1-3, β-defensin-2 and β-defensin-1 levels in patients with various gastroduodenal diseases (mean±SD).

	Human neutrophil peptides 1-3 (ng/mL)	b-defensin 2 (pg/mL)	b-defensin-1 (ng/mL)
Chronic gastritis	520.8±0.0	250.4±4.1	8.68±.08
Gastric ulcer	512.1±5.3	225.3±2.6	8.81±.26
Duodenal ulcer	560.4±21.9	269.8±6.5	8.37±.14
Benign gastric polyp	606.4±9.5	206.2±0.0	7.81±.32
Normal mucosa	552.7±9.5	196.3±5.4	7.08±.88

Table 2 Plasma human neutrophil peptides 1-3, β-defensin-2 and β-defensin-1 levels and H pylori status (mean±SD).

	H pylori-infected	H pylori-uninfected
Human neutrophil peptides 1-3 (ng/mL)	544.2±6.4	518.3±3.1
b-defensin 2 (pg/mL)	286.5±5.8	238.5±3.4
b-defensin 1 (ng/mL)	7.66±0.94	8.13±0.71

Table 3 Plasma pepsinogen I and II levels, pepsinogen I/II ratio and gastrin concentrations in patients with various gastroduodenal diseases (mean±SD).

	Pepsinogen I (ng/mL)	Pepsinogen II (ng/mL)	Pepsinogen I/II ratio	Gastrin (pg/mL)
Chronic gastritis	52.0±26.5	19.5±9.8	3.3±1.9	84.9±41.3
Gastric ulcer	67.1±31.2	31.4±12.5	2.4±1.3	69.3±35.9
Duodenal ulcer	76.7±20.2	18.1±8.9	4.5±0.8	69.2±34.6
Benign gastric polyp	49.0±29.1	17.3±16.9	4.0±2.8	57.1±30.4
Normal mucosa	46.7±26.2	9.2±5.4	5.2±1.5	48.5±22.1

Table 4 Plasma pepsinogen I and II levels, pepsinogen I/II ratio and gastrin concentrations with respect to H pylori status.

	Pepsinogen I (ng/mL)	Pepsinogen II (ng/mL)	Pepsinogen I/II ratio	Gastrin (pg/mL)
H pylori-infected	62.9±25.6	23.5±11.4	3.1±2.5	76.1±39.7
H pylori-uninfected	42.5±23.2	8.6±4.9	5.2±3.4	56.2±27.7

Table 5 Correlation coefficients between each parameter.

	Pepsinogen I (ng/mL)	Pepsinogen II (ng/mL)	Pepsinogen I/II ratio	Gastrin (pg/mL)
Human neutrophil peptides 1-3	-0.492	0.043	-0.418	-0.265
b-defensin 2	0.073	0.297	-0.321	0.087
b-defensin 1	-0.114	0.023	-0.175	0.14