Epidemiology and outcome of Crohn’s disease in a teaching hospital in Riyadh

Table 1 Demographic characteristics of patients with Crohn’s disease in KKUH, Riyadh, Saudi Arabia (n = 77)

	All patients	Active	On remission
Number	77	34 (44%)	43 (56%)
Total males	33 (42.9%)	15 (44%)	18 (42%)
Total females	44 (57.1%)	19 (56%)	25 (58%)
Age (range), yr	11-70	11-55	11-70
Mean age, yr	25.3 ± 11.3	22.9 ± 8.3	27.3 ± 13.2
Nationality (Saudi/non-Saudi)	71/6	32/2	39/4

Table 2 Clinical features of Crohn’s disease in KKUH n (%)

	All patients, n = 77	Active Crohn's, n = 34	Remission, n = 43
Abdominal pain	67 (87)	29 (85)	38 (88)
Diarrhea	60 (78)	27 (79)	33 (77)
Weight loss	41 (53)	23 (68)	18 (42)
Anorexia	22 (29)	10 (29)	12 (28)
Fever	20 (26)	8 (24)	12 (28)
Rectal bleeding	19 (25)	5 (15)	14 (32)
Normal physical examination	32 (42)	10 (29)	22 (51)
Abdominal tenderness	45 (58)	24 (71)	21 (49)
Palpable mass	8 (10)	3 (9)	5 (12)

Table 3 Colonoscopic, biopsy, small bowel enema findings and CT scan results of Crohn's disease in KKUH n (%)

	All patients	Active Crohn's	Remission
Colonoscopy	n = 76	n = 33	n = 43
Normal	18 (24)	8 (24)	10 (23)
Abnormal	58 (76)	25 (76)	33 (77)
Biopsy	n = 77	n = 34	n = 43
Normal	0	0	0
Abnormal	77 (100)	34 (100)	43 (100)
Enteroclysis	n = 77	n = 34	n = 43
Normal	8 (11)	5 (15)	3 (7)
Abnormal	69 (89)	29 (85)	40 (93)
CT scan	n = 77	n = 34	n = 43
Normal	9 (12)	9 (26)	0
Abnormal	68 (88)	25 (74)	43 (100)

Table 4 Initial laboratory results of Crohn’s disease patients at KKUH (all patients vs active vs on remission)

	All patients	Active Crohn’s	Remission
WBC count	9.06 ± 3.95	8.57 ± 4.43	9.42 ± 3.58
Hemoglobin	10.8 ± 1.89	10.97 ± 1.61	10.72 ± 2.12
Platelets	429.9 ± 161	422.5 ± 145.2	435.4 ± 176.1
ESR	42.8 ± 27.8	34.4 ± 22.9	49.5 ± 26.6
Albumin	30.7 ± 8.9	30.4 ± 9.9	30.97 ± 8.21

Table 5 Comparison of initial and last follow-up laboratory results of Crohn’s disease patients who went into remission

	Initial visit	Last follow-up	P value
WBC count	9.42 ± 3.58	8.36 ± 3.4	0.1629
Hemoglobin	10.72 ± 2.12	12.4 ± 1.78	0.0001
Platelets	435.4 ± 176.1	396.4 ± 132.02	0.2485
ESR	49.5 ± 26.6	29.9 ± 26.01	0.0009
Albumin	30.97 ± 8.21	33.5 ± 7.97	0.1508

Table 6 Comparison of initial and last follow-up laboratory results of Crohn’s disease patients who remained active

	Initial visit	Last follow-up	P value
WBC count	8.57 ± 4.43	8.35 ± 3.04	0.812
Hemoglobin	10.97 ± 1.61	11.2 ± 2.3	0.6344
Platelets	422.5 ± 145.2	388.5 ± 122.5	0.3005
ESR	34.4 ± 22.9	33.05 ± 24.4	0.8148
Albumin	30.4 ± 9.9	30.55 ± 7.67	0.9445