Brief Reports
Copyright ©The Author(s) 2004.
World J Gastroenterol. Mar 1, 2004; 10(5): 733-736
Published online Mar 1, 2004. doi: 10.3748/wjg.v10.i5.733
Table 1 Demographic characteristics and clinical response
VariableNRa (n = 7)PR (n = 10)CR (n = 8)P value
Sex (F:M)4:38:26:2NS
Age (mean ± SD)57.2 ± 6.751.4 ± 7.244.4 ± 15.7NS
Serum ALT levels
(mean ± SD)68.5 ± 39.595.4 ± 67.990.9 ± 40.1NS
Liver histology
Activity index
A1431
A2267NS
A3110
Fibrosis index
F1355
F2332NS
F3121
Serum viral loadb
Low166< 0.05
High642
Genotype
Ib672< 0.05
Others136
Table 2 Viral load in PBMC and clinical response
VariableNRa (n = 7)PR (n = 10)CR (n = 8)P value
Viral loadb (pretreatment)
000
1+021NS
2+787
Decrease of HCV-RNA by IFN-βc
Yes198< 0.05
No610

  • Citation: Mochizuki K, Kagawa T, Takashimizu S, Kawazoe K, Kojima SI, Nagata N, Nakano A, Nishizaki Y, Shiraishi K, Itakura M, Watanabe N, Mine T, Matsuzaki S. Effect of in vitro interferon-beta administration on hepatitis C virus in peripheral blood mononuclear cells as a predictive marker of clinical response to interferon treatment for chronic hepatitis C. World J Gastroenterol 2004; 10(5): 733-736
  • URL: https://www.wjgnet.com/1007-9327/full/v10/i5/733.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v10.i5.733