Effect of parenteral and enteral nutrition combined with octreotide on pancreatic exocrine secretion of patients with pancreatic fistula

Table 1 Effect of PN and/or EN combined with octreotide on pancreatic juice, protein and amylase secretion

Group	n	Pancreatic juice (mL/d)			Protein (mg/L)			Amylase (U/L)
		d 1	d 4	d 7	d 1	d 4	d 7	d 1	d 4	d 7
PN	9	86 ± 35	77 ± 49	81 ±31	34 ± 17	30 ± 17	29 ± 17	4 268 ± 1 361	4 026 ± 1 131	4 468 ± 1 487
PN + Oc- treotide	9	64 ± 21a	58 ± 19a	60 ±23a	25 ± 17a	21 ± 17a	23 ± 17a	3 268 ± 1 031a	3 342 ± 1 116a	3 081 ± 1 213a
EN	8	91 ± 73	81 ± 73	93 ± 73	36 ± 24	37 ± 24	35 ± 24	4 761 ± 987	4 361 ± 1 023	4 276 ± 912
EN + Oc- treotide	8	67 ± 29c	61 ± 39a	66 ± 34a	27 ± 12a	31 ± 17	30 ± 10	3 963 ± 1 104a	3 566 ± 1 001a	3 363 ± 1 221a

Oct: Octreotide;

^aP < 0.05 vs PN group ;

^cP < 0.05 vs EN group.

Table 2 Effect of PN and/or EN combined with octreotide on HCO₃^-, K⁺, Na⁺ and Cl^- secretion in pancreatic juice (mmol/L)

Group	n	HCO3-			K+			Na+			Cl-
		d 1	d 4	d 7	d 1	d 4	d 7	d 1	d 4	d 7	d 1	d 4	d 7
PN	9	73 ± 37	69 ± 31	71 ± 32	32 ± 19	28 ± 12	31 ± 17	123 ± 33	133 ± 31	126 ± 43	61 ± 34	63 ± 31	58 ± 24
PN+Oct	9	54 ± 34a	57 ± 24a	59 ± 31a	22 ± 11a	19 ± 9a	21 ± 17a	87 ± 53a	78 ± 67a	93 ± 55a	49 ± 13a	42 ± 21a	49 ± 17a
EN	8	79 ± 44	81 ± 35	83 ± 47	37 ± 17	36 ± 13	34 ± 19	131 ± 44	129 ± 33	139 ± 28	73 ± 37	71 ± 43	68 ± 31
EN+Oct	8	65 ± 23c	61 ± 33c	57 ± 37c	25 ± 15c	28 ± 11c	28 ± 13	101 ± 63c	95 ± 79c	91 ± 73c	51 ± 15c	49 ± 21c	53 ± 35c

Oct: Octreotide;

^aP < 0.05 vs PN group;

^cP < 0.05 vs EN group.