Effect of extracts of trichosanthes root tubers on HepA-H cells and HeLa cells

Table 1 Cytotoxic activity of EOT and TCS in HepA-H cells (n = 4, mean ± SD)

Drug	Concentration (mg/L)	Inhibitory rate (%)
		24 h	36 h	48 h
EOT	0.1	-3.1 ± 2.9	19.1 ± 2.6	15.7 ± 0.8
	1.0	-3.6 ± 8.1	7.9 ± 11.5	5.1 ± 2.6
	10	-25.0 ± 1.7	6.8 ± 0.1	3.8 ± 3.6
	100	9.6 ± 3.3	21.0 ± 2.2	16.2 ± 6.3
	500	7.6 ± 7.6	17.0 ± 3.0	13.4 ± 0.7
TCS	0.1	-19.9 ± 6.7	6.9 ± 5.2	-3.7 ± 4.9
	1.0	-6.1 ± 6.4	4.7 ± 0.6	7.4 ± 2.7
	10	-16.1 ± 19.1	0.7 ± 2.4	-11.4 ± 4.7
	100	-6.8 ± 1.0	11.9 ± 4.1	2.6 ± 2.3
	500	-3.4 ± 3.3	10.8 ± 5.2	5.9 ± 3.8

Table 2 Cytotoxic activity of EOT and TCS in HeLa cells (n = 4, mean ± SD)

Drug	Concentration (mg/L)	Inhibitory rate (%)
		24 h	36 h	48 h
EOT	0.1	3.4 ± 4.1	9.7 ± 7.0	9.9 ± 3.1
	1.0	4.5 ± 3.7	11.1 ± 2.0	11.3 ± 1.9
	10	16.3 ± 3.2	20.9 ± 6.8	29.4 ± 4.1
	100	36.7 ± 4.0	44.2 ± 1.7	54.6 ± 3.0
	500	57.9 ± 3.4	71.8 ± 3.9	89.4 ± 1.9
TCS	0.1	2.2 ± 1.7	2.9 ± 2.7	4.4 ± 3.1
	1.0	2.9 ± 2.0	5.5 ± 1.2	6.0 ± 2.7
	10	16.4 ± 4.1	6.7 ± 2.4	13.0 ± 3.3
	100	26.3 ± 2.5	29.3 ± 3.9	47.9 ± 5.2
	500	39.6 ± 4.8	53.8 ± 4.0	70.2 ± 2.9