Liver Cancer
Copyright ©The Author(s) 2004.
World J Gastroenterol. May 15, 2004; 10(10): 1425-1430
Published online May 15, 2004. doi: 10.3748/wjg.v10.i10.1425
Table 1 Clinicopathologic characteristics of 32 Patients
Clinicopathologic parametersNumber%
Age
≤ 45 years1443.8
> 45 years1856.2
Gender
Male2681.2
Female618.8
Gross type
Massive1546.9
Nodular1753.1
Tumor size
≤ 5 cm515.6
> 5 cm2784.4
Cellular differentiation
I412.5
II1753.1
III515.6
IV618.8
Degree of invasion
T1 + T21237.5
T3 + T42062.5
Stage
I + II1031.2
III + IV2268.8
Lymph node metastasis
Present487.5
Absent2812.5
Portal invasion
With39.4
Without2990.6
Infiltration
Present1237.5
Absent2062.5
Table 2 Relationship among p27, PCNA, and cytoplasmic p27staining with clinicopathologic features
Parametersp27 LI (%)PPCNA LI (%)PCytoplasmic p27 LI (%)P
Gross type
Massive20.5 ± 13.10.03746.4 ± 13.40.24925.9 ± 18.90.221
Nodular35.7 ± 23.452.3 ± 14.717.9 ± 17.3
Tumor size
≤ 5 cm23.8 ± 14.40.64538.1 ± 10.70.04727.0 ± 24.10.481
> 5 cm28.4 ± 20.951.7 ± 13.920.6 ± 17.4
Cellular differentiation
Well or moderate29.7 ± 21.40.43845.7 ± 13.80.03123.2 ± 18.00.498
Poor23.8 ± 17.156.9 ± 12.618.6 ± 19.1
Degree of invasion
T1 + T232.6 ± 23.30.28551.1 ± 14.70.6433.0 ± 22.30.019
T3 + T424.7 ± 17.548.6 ± 14.414.8 ± 11.1
Stage
I + II33.6 ± 25.60.26148.0 ± 12.90.68835.3 ± 23.90.029
III + IV24.9 ± 16.750.2 ± 15.015.4 ± 10.7
Infiltration
Present18.3 ± 18.80.03644.4 ± 12.30.11719.0 ± 18.30.536
Absent33.3 ± 18.752.6 ± 14.723.2 ± 18.5
Lymphocyte metastasis
With25.5 ± 2.60.56556.0 ± 14.90.33916.0 ± 10.60.518
Without27.9 ± 21.348.6 ± 14.222.4 ± 19.1
Portal invasion
Present14.3 ± 12.70.22958.3 ± 12.00.26713.0 ± 11.80.398
Absent29.1 ± 20.148.6 ± 14.322.5 ± 18.7
Table 3 Univariate and multivariate analyses of individual parameters
VariablesP values
UnivariateMultivariate
Age0.1500.016
Tumor size0.5130.678
Carcinoma differentiation0.4150.628
Stage0.2000.080
Lymphocyte metastasis0.8210.050
Infiltration0.3170.849
Portal invasion0.0210.619
p270.0330.009
Cytoplasmic p270.1140.624
PCNA0.9150.282