Evaluation of the hepatitis B virus in hepatitis B surface antigen by hepatitis B virus deoxyribonucleic acid measured with polymerase chain reaction

doi:10.3748/wjg.v4.iSuppl2.85

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 1998; 4(Suppl2): 85-85
Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.85

Evaluation of the hepatitis B virus in hepatitis B surface antigen by hepatitis B virus deoxyribonucleic acid measured with polymerase chain reaction

Zhen Zheng, Shuang-Wang Yang, Wei Xiao, Pei Sun, Xin-Jian Li, Ya-Qin Hu

Zhen Zheng, Shuang-Wang Yang, Wei Xiao, Pei Sun, Xin-Jian Li, Ya-Qin Hu, Department of Gastroenterology of pLA 454 Hospital, Nanjing 210002, Jiangsu Province, China

Author contributions: All authors contributed equally to the work.

Correspondence to: Dr. Zhen Zheng, Department of Gastroenterology of pLA 454 Hospital, Nanjing 210002, Jiangsu Province, China

Received: June 11, 1998
Revised: July 21, 1998
Accepted: August 13, 1998
Published online: October 15, 1998

Abstract

AIM: To evaluated whether the nagative HBsAg inpatients carry HBV in the department of gastroenterology in our Hospital.

METHODS: The HBV DNA was measured with PCR technique 119 negative HBsAg digestive inpatients and compared with negative HBsAg hepatitis inpatients.

RESULTS: The results showed that 52.1% of the digestive inpatients in he department of gastroenterology were positive HBVM (HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc), and 30.3% HBV DNA was positive in the patients. This two indexes were markedly lower compared with hepatitis. The difference of the rate of positive HBV DNA in the two groups was only in the HBV infective model of negative HBVM.

CONCLUSION: The results suggested that there were HBV carriers in negative HBsAg inpatients in the department of gastroenterology, and positive HBVM patients of the two groups actually come from the same group.

Key Words: Hepatitis B virus, DNA, viral, HBsAg, Polymerase chain reaction

Citation: Zheng Z, Yang SW, Xiao W, Sun P, Li XJ, Hu YQ. Evaluation of the hepatitis B virus in hepatitis B surface antigen by hepatitis B virus deoxyribonucleic acid measured with polymerase chain reaction. World J Gastroenterol 1998; 4(Suppl2): 85-85
URL: https://www.wjgnet.com/1007-9327/full/v4/iSuppl2/85.htm
DOI: https://dx.doi.org/10.3748/wjg.v4.iSuppl2.85

Footnotes

E- Editor: Li RF