Copyright
©The Author(s) 1998. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 15, 1998; 4(Suppl2): 123-123
Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.123
Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.123
Study on the therapeutic effect of all-trans retinoic acid and malotilate on CCl4-induced hepatic fibrosis of rats
Fei Yin, Shu-Kun Yao, Zhi-Hui Li, Hua-Cun Shi, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, Hebei Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Fei Yin, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, Hebei Province, China
Received: July 8, 1998
Revised: August 17, 1998
Accepted: September 7, 1998
Published online: October 15, 1998
Revised: August 17, 1998
Accepted: September 7, 1998
Published online: October 15, 1998
Abstract
METHODS: The effect of all-trans retinoic acid and malotilate on CCl4-induced hepatic fibrosis of rats was investigated, using colchicine as control, Immunohistochemical stain of I, III, IV, V collagen and desmin, computer imaging analysis and electronic microscopy were applied to study the effect.
RESULTS: All-trans retinoic acid and malotilate had mild effect of fibrolysis, compared to colchicine. Additionally, CCl4-induced fibrosis of rats had restored to some degree without treatment.
- Citation: Yin F, Yao SK, Li ZH, Shi HC. Study on the therapeutic effect of all-trans retinoic acid and malotilate on CCl4-induced hepatic fibrosis of rats. World J Gastroenterol 1998; 4(Suppl2): 123-123
- URL: https://www.wjgnet.com/1007-9327/full/v4/iSuppl2/123.htm
- DOI: https://dx.doi.org/10.3748/wjg.v4.iSuppl2.123
Footnotes
E- Editor: Li RF