Copyright ©The Author(s) 2021.
World J Gastroenterol. Apr 14, 2021; 27(14): 1406-1418
Published online Apr 14, 2021. doi: 10.3748/wjg.v27.i14.1406
Figure 1
Figure 1 Gut dysbiosis induced by the immune response to severe acute respiratory syndrome coronavirus 2 in the gastrointestinal tract increases gut permeability, which in turn increases spike protein trafficking. Spike protein was reported to act as a superantigen that links the T-cell receptor and major histocompatibility complex II on antigen-presenting cells. ACE2: Angiotensin converting enzyme 2; S-protein: Spike protein; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2.