Copyright ©The Author(s) 2020.
World J Gastroenterol. Jul 7, 2020; 26(25): 3562-3576
Published online Jul 7, 2020. doi: 10.3748/wjg.v26.i25.3562
Table 2 Enteroendocrine cell models
MouseSTC-1Duodenal secretin tumour cellsGLP-1, GLP-2, CCK, GIP, PYY,Heterogeneous cell population; respond to glucose, amino acids, fatty acids and neural stimuli; poor expression of CaSR
GLUTagColonic tumourGLP-1, GLP-2, CCKSubcloned homogenous cells; respond to glucose, bile acids, fatty acids, amino acids
HumanNCI-H716Colorectal carcinomaGLP-1, GLP-2Heterogeneous cell population; poorly differentiated; respond to glucose, fatty acids, protein hydrolysates
HuTu-80Duodenal carcinomaGLP-1, PYY, GIP, CCKRespond to antioxidant compounds, sweet and bitter substances