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©The Author(s) 2020.
World J Gastroenterol. May 14, 2020; 26(18): 2203-2220
Published online May 14, 2020. doi: 10.3748/wjg.v26.i18.2203
Published online May 14, 2020. doi: 10.3748/wjg.v26.i18.2203
Figure 5 Folic acid improves hepatic one-carbon metabolism in rats with high-fat diet-induced steatohepatitis.
A: Serum folic acid levels in each group; C and D: mRNA levels of MAT1A and ALDH1L1 in each group; B and E: Protein levels of MAT1A in each group. All the data are expressed as the mean ± SE (n = 3-8). aP < 0.05 vs con group bP < 0.01 vs con group; cP < 0.05 vs HFD group; dP < 0.01 vs HFD group. HFD: High-fat diet; MAT1A: Methionine adenosyltransferase 1A.
- Citation: Xin FZ, Zhao ZH, Zhang RN, Pan Q, Gong ZZ, Sun C, Fan JG. Folic acid attenuates high-fat diet-induced steatohepatitis via deacetylase SIRT1-dependent restoration of PPARα. World J Gastroenterol 2020; 26(18): 2203-2220
- URL: https://www.wjgnet.com/1007-9327/full/v26/i18/2203.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i18.2203