DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p

Figure 4 MiR-432-5p regulates PPME1 expression in pancreatic carcinoma. A: Three possible mRNAs regulated by miR-432-5p were selected and are presented in a Venn diagram; B and C: The expression levels of three target mRNAs were assessed after overexpression of miR-432-5p; D and E: The protein levels of three possible proteins were assessed after overexpression of miR-432-5p; F: The binding sites between PPME1 and miR-432-5p; G: Luciferase activity of miR-432-5p mimic with PPME1-WT or PPME1-MUT; H and I: PPME1 expression regulation by miR-432-5p mimic or inhibitor in Hs766T cells; J: PPME1 expression in pancreatic carcinoma tissues; K: MiR-432-5p inversely regulates PPME1 expression. ^aP < 0.05, ^bP < 0.01.