DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p

Figure 3 DNAH17-AS1 acts as a sponge for miR-432-5p in pancreatic carcinoma cells. A: Subcellular fractionation assay was performed to identify the location of DNAH17-AS1 in Hs766T cells; B: The binding sites between DNAH17-AS1 and miR-432-5p; C: Luciferase activity of miR-432-5p mimic with DNAH17-AS1-WT or DNAH17-AS1-MUT; D: MiR-432-5p expression is regulated by si-DNAH17-AS1 in Hs766T cells. E-H: Cell proliferation (E), migration (F), invasion (G), and apoptosis (H) in Hs766T cells treated with miR-432-5p mimic or si-DNAH17-AS1 and miR-432-5p inhibitor. ^aP < 0.05, ^bP < 0.01.