Opinion Review
Copyright ©The Author(s) 2019.
World J Gastroenterol. Sep 7, 2019; 25(33): 4805-4813
Published online Sep 7, 2019. doi: 10.3748/wjg.v25.i33.4805
Table 1 Prospective studies on the prevalence of erosive esophagitis in obese patients
PublicationYearNumber of subjectsPrevalence of EE (%)Comments
Verset et al[18]199714730.6High incidence of peptic lesions that were mainly asymptomatic
Ortiz et al[9]200613818.8Sensitivity of heartburn as diagnostic criterion of GERD was 29.3%, with a specificity of 85.7%
Asymptomatic GER (abnormal esophageal acid exposure and/or EE) more common than symptomatic GER
Csendes et al[10]200742626.3Out of the 112 EE patients, 77 (68.7%) reported GERD symptoms
Merrouche et al[11]2007946.446% of patients had abnormal 24-pH study
Dutta et al[19]20091018.96.9% EE in age- and sex-matched non-obese control subjects
Tai et al[20]201026032.3Increased waist circumference, insulin resistance, and presence of reflux symptoms independent risk factors for EE
Martin-Perez et al[21]2014884.5Esophageal pH monitoring tests positive in 65% of patients
Absence of symptoms did not rule out abnormal esophageal function tests
Carabotti et al[24]20151424.2Majority of endoscopic lesions were asymptomatic
Mora et al[23]201619617.3Esophageal pH-metry abnormal in 54.2% of patients
Symptoms not enough to diagnose underlying GERD or EE
Sharara et al[24]201924233.9Anthropometric data and GERD questionnaires have limited accuracy for EE
12.3% of patients with low GERDQ (< 8) had EE