Systematic Reviews
Copyright ©The Author(s) 2018.
World J Gastroenterol. Jan 7, 2018; 24(1): 124-138
Published online Jan 7, 2018. doi: 10.3748/wjg.v24.i1.124
Table 2 Summarized recommendations for colorectal cancer screening in average-risk individuals, published in Europe between 2007 and 2017
ContinentCountry/AssociationYearAgeScreening tests recommendedRecommendationNote
EuropeScotland: TIS2011 (revised in 2016)Age not mentionedFIT (quantitative) (interval not mentioned)Grade A recommendationPerformance of FS unsure in the Scottish population. Colonoscopy and CT colonography are not recommended
Germany: GGPO2014≥ 50Preferred test: Colonoscopy (10 yr) If refused by individual: FS (5 yr) + annual FOBT OR Annual FOBTColonoscopy: Grade B recommendation; 3b level of evidence. FS: Grade B recommendation; 2b level of evidence. Adding FOBT to FS: Grade B recommendation; 3b level of evidence. FOBT as a screening test: Good clinical practiceGeneral use of FIT is not recommended, but FIT can be used instead of gFOBT if it has a proven high specificity (> 90%) and sensitivity. Genetic stool tests, CT colonography, MR-colonography and capsule endoscopy are not recommended.
Spain: SEOM201450-74FIT every 2 yr OR, depending on available resources, annual or biennial gFOBT OR FS (5 yr) OR colonoscopy (every 10 yr)Grade B (moderate) quality of evidence, except for FOBT every 2 yr (grade A quality of evidence)Combination of gFOBT and FS, and CT colonography are not recommended
European Guidelines201350-74Recommended test: gFOBT/FIT (1-2 yr)Recommendation based on good evidence for gFOBT, reasonable evidence for FIT and FS, and limited evidence for colonoscopyEvidence supports FIT superiority compared to gFOBT
Other options include colonoscopy (10-20 yr) OR FS (10-20 yr)