Copyright ©The Author(s) 2017.
World J Gastroenterol. Sep 28, 2017; 23(36): 6571-6592
Published online Sep 28, 2017. doi: 10.3748/wjg.v23.i36.6571
Table 2 Drugs useful in treating nonalcoholic steatohepatitis - A neck-to-neck comparison of findings from two different meta-analytic studies
Sawangjit et al[244]Singh et al[243]
FibrosisOCA1 improves fibrosis.PTX2, TZDs plus Metformin2, TZDs plus Losartan2 might potentially be effective.PTX1 and OCA1 improve fibrosis
Resolution of NASHTZDs1 and Vitamin E1 use is associated with resolution of NASHVitamin E1, TZDs1, and OCA1 improve ballooning degeneration
NASPTX1, OCA1, vitamin E1, and TZDs1 improve NAS
SteatosisPTX1, Vitamin E2, TZD1 and OCA2 significantly improve steatosis
Lobular inflammationPTX1, TZDs1 and OCA2 significantly improve lobular Inflammation