Folfirinox in elderly patients with pancreatic or colorectal cancer-tolerance and efficacy

doi:10.3748/wjg.v22.i42.9378

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Nov 14, 2016 (publication date) through Jul 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2016; 22(42): 9378-9386
Published online Nov 14, 2016. doi: 10.3748/wjg.v22.i42.9378

Table 2 Observed toxicity according Common Terminology Criteria for Adverse Events v 4.03 (n = 52) n (%)

	CTCAE v 4.03
	All grades	Severe¹
Hematological
Anemia	28 (53.8)	5 (9.6)
Neutropenia	24 (46.2)	17 (32.7)
Thrombocytopenia	14 (26.9)	3 (5.8)
Non Hematological
Diarrhea	35 (67.3)	13 (25.0)
Nausea and vomiting	22 (42.3)	5 (9.6)
Asthenia	49 (94.2)	5 (9.6)
Peripheral Neutropenia	17 (32.7)	4 (7.7)
Hepatic toxicity	4 (7.7)	1 (1.9)

¹Grade 3-4 according to the CTCAE version 4.03. CTCAE: Common Terminology Criteria for Adverse Events.

Citation: Guion-Dusserre JF, Bertaut A, Ghiringhelli F, Vincent J, Quipourt V, Marilier S, Tharin Z, Bengrine-Lefevre L. Folfirinox in elderly patients with pancreatic or colorectal cancer-tolerance and efficacy. World J Gastroenterol 2016; 22(42): 9378-9386
URL: https://www.wjgnet.com/1007-9327/full/v22/i42/9378.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i42.9378