Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells
Ying Li, Yu-Ying Hu, Lin Chen, Jian-Ming Li, Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China
Yu-Hong Liu, Department of Pathology, Baoan Hospital, Southern Medical University, Shenzhen 518101, Guangdong Province, China
Jian-Ming Li, Department of Pathology, Soochow University Medical School, Suzhou 215123, Jiangsu Province, China
Author contributions: Li Y and Liu YH contributed equally to this work; Li Y, Liu YH and Li JM contributed to study concept and design; Li Y, Hu YY and Chen L contributed to data acquisition; Li Y, Hu YY and Li JM contributed to statistical analysis; Li Y and Li JM contributed to data analysis and interpretation; Li Y and Li JM contributed to drafting of the manuscript for important intellectual content; Liu YH contributed to technical or material support; Li JM contributed to obtaining funding; and Li JM contributed to study supervision.
Supported by National Natural Science Foundation of China, No. 81525020, No. 81502033, No. 81272300 and No. 31570753.
Institutional review board statement: This study was approved by the Institutional Review Board of Nanfang Hospital, Southern Medical University, China.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at firstname.lastname@example.org. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jian-Ming Li, MD, PhD, DSc, Professor, Chief, Department of Pathology, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Road North, Guangzhou 510515, Guangdong Province, China. email@example.com
Received: May 19, 2016
Peer-review started: May 20, 2016
First decision: July 12, 2016
Revised: July 29, 2016
Accepted: August 19, 2016
Article in press: August 19, 2016
Published online: October 14, 2016