Clinical characteristics of drug-induced liver injury and primary biliary cirrhosis

doi:10.3748/wjg.v22.i33.7579

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 7, 2016; 22(33): 7579-7586
Published online Sep 7, 2016. doi: 10.3748/wjg.v22.i33.7579

Table 7 Comparison of autoantibodies between typed drug-induced liver injury and primary biliary cirrhosis patients n (%)

	Autoantibodies	ANA	AMA	SMA	AMA-M2	AMA-M4	AMA-M9
Hepatocellular type DILI (n = 90)	43 (47.7)^a	41 (45.5)^a	2 (2.22)^a	2 (2.22)	2 (2.22)^a	0^a	1 (1.11)^a
Cholestatic type DILI (n = 20)	10 (50.0)^a	8 (40.0)^a	2 (10.0)^a	1 (5.00)	1 (5.00)^a	0^a	1 (5.00)
Mixed type DILI (n = 14)	6 (42.8)^a	6 (42.8)^a	0^a	1 (7.14)	0^a	1 (7.14)	1 (7.14)
PBC (n = 116)	106 (91.3)	98 (84.4)	98 (84.4)	2 (1.72)	98 (84.4)	34 (29.3)	19 (16.3)

^aP < 0.05 vs the PBC group. DILI: Drug-induced liver injury; PBC: Primary biliary cirrhosis; ANA: Antinuclear antibody; AMA: Antimitochondrial antibody; SMA: Anti-smooth muscle antibody.

Citation: Yang J, Yu YL, Jin Y, Zhang Y, Zheng CQ. Clinical characteristics of drug-induced liver injury and primary biliary cirrhosis. World J Gastroenterol 2016; 22(33): 7579-7586
URL: https://www.wjgnet.com/1007-9327/full/v22/i33/7579.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i33.7579