miR-122 negatively correlates with liver fibrosis as detected by histology and FibroScan

Figure 2 Relative miRNA expression in relation to fibrosis stage, detected in the biopsy samples of various etiologic backgrounds. The level of miR-122 is reduced in stage F4 as compared with stage F0 (P < 0.04), analyzed using a nonparametric Kruskal-Wallis analysis of variance and median test. The upper dotted line indicates twofold elevation in expression; the lower dotted line signifies a one-half reduction of expression.