NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease

Table 2 Demographic, clinical data and genotype-phenotype correlations in ulcerative colitis patients n (%)

Variables	All subjects	Non carriers	Carriers	P value
HC	114	102 (89.47)	12 (10.52)	0.120
UC patients	46	42(91.3)	4(8.7)	0.726
Sex (F/M)	30/16	27/15	3/1	0.667
Age at diagnosis	36.86 ± 12.30	36.92 ± 11.34	36.25 ± 22.60
A1	1 (2.1)	1	0	0.916
A2	31 (67.4)	28	3
A3	14 (30.5)	13	1
Location
E1: proctitis	9 (20)	9	0	0.115
E2: distal colitis	19 (41.5)	16	3
E3: extensive colitis	18 (39)	17	1
Resection Surgery	4 (9)	3	1	0.225
EIM	11 (24)	11	0	0.240
Positive family history for UC	11 (24)	10	1	0.957

A1 < 16, A2 = 16-40, A3 40 years according Montreal classification. UC: Ulcerative colitis; HC: Healthy controls; EIM: Extra intestinal manifestations.