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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 21, 2014; 20(31): 10790-10801
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10790
Figure 1
Figure 1 Models that explain tumor development. A: The stochastic model states that every cell has the potential to be the “the cell of origin” of a tumor; B: The “cancer stem cell hypothesis” proposes that tumor evolution is based on stem cells with ‘deregulated’ signaling pathways. EMT: Epithelial-mesenchymal transition.