Endoscopic papillary large balloon dilation for the removal of bile duct stones

Table 4 Comparison between endoscopic papillary large balloon dilation with and without endoscopic sphincterotomy n (%)

	EPLBD with EST	No. of studies	EPLBD without EST	No. of studies	P value
No. of procedures	2511	30	413	3
Mean of mean age, yr	69.6 ± 8.61	29	70.3 ± 2.31	3	0.808
Periampullary diverticulum	773 (36.7)	23	122 (33.2)	2	0.186
Initial success	1745 (84.0)	24	285 (76.2)	3	< 0.001
Success without EML	2077 (83.2)	30	306 (76.7)	3	0.001
Use of EML	353 (14.1)	30	86 (21.6)	3	< 0.001
Overall success	2407 (96.5)	30	388 (97.2)	3	0.432
Overall adverse events	209 (8.3)	30	29 (7.0)	3	0.370
Pancreatitis, total; M/Mod/S/F	61; 51/9/0/1 (2.4)	30	16; 14/2/0/0 (3.9)	3	0.089
Bleeding, total; M/Mod/S/F	91; 75/11/2/2 (3.6)2	30	8; 7/1/0/0 (1.9)	3	0.079
Perforation, total; M/Mod/S/F	15; 3/6/3/3 (0.6)	30	2; 0/2/0/0 (0.5)	3	1.000
Other adverse events	42 (1.7)	30	3; 3/0/0/0 (0.7)	3	0.148
AE-related surgery	6 (0.2)	30	0 (0)	3	1.000
AE-related death	6 (0.2)	30	0 (0)	3	1.000

¹mean ± SD;

²One case of bleeding was not graded for severity. M: Mild; Mod: Moderate; S: Severe; F: Fatal; EPLBD: Endoscopic papillary large balloon dilation; EST: Endoscopic sphincterotomy; EML: Endoscopic mechanical lithotripsy; AE: Adverse event.